<p><strong>Efek pemberian <em>astaxanthin (Haematococcus pluvialis)</em> terhadap ukuran diameter pada model ulkus traumatikus</p><strong><p><em>The effect of astaxanthin (Haematococcus pluvialis) on diameter measurement in traumatic ulcer model</p></em><strong>

نویسندگان

چکیده

ABSTRAK Pendahuluan: Prevalensi ulser rongga mulut di Indonesia tinggi (96,6%). Astaxanthin yang berasal dari mikroalga hijau Haematococcus pluvialis merupakan salah satu alternatif pengobatan karena adanya sifat antioksidan dan efek anti inflamasinya. Tujuan penelitian menganalisis pengaruh efektivitas pemberian astaxanthin terhadap selisih ukuran diameter hari ke-1 ke-3 pada model ulkus traumatikus. Metode: Sampel 30 ekor tikus putih Wistar dibagi secara acak menjadi 5 kelompok diberi perlakuan traumatikus kemudian terapi selama 3 sesuai dengan masing-masing: K- (kelompok kontrol basis gel); K+ asam hialuronat); P1 (pemberian 0,1%); P2 0,5%); P3 1%). Data hasil selanjutnya dilakukan uji one way ANOVA dilanjutkan Post Hoc LSD p=0,05. Hasil: Hasil analisis parametrik One Way menunjukkan terdapat perbedaan bermakna (p<0,05) ke-3. Uji antara (5,300 ± 2,832) dibandingkan (2,297 1,045), P1(1,740 1,168), P2(1,993 0,738), (2,448 1,320). Simpulan: Terdapat gel dalam menurunkan proses penyembuhan Kata kunci: antiinflamasi; astaxanthin; haematococcus ; ABSTRACT Introduction: The prevalence of traumatic ulcers in is high Astaxanthin, derived from the green microalgae Pluvialis, alternative treatments for ulcer healing due to its potent antioxidant and anti-inflammatory effect. This study aimed analyze astaxanthin’s effectiveness on difference day 1 a model. Methods: Samples rats were randomly divided into groups which treated with then days according their respective groups: (control group given base); hyaluronic acid); (application 0.1% astaxanthin); 0.5% 1% astaxanthin). data results carried out test, test proceeded Results: statistical parametric using showed significant 3. between compare Conclusions: There an effect giving reducing process ulcer. Keywords: anti-inflammatory; pluvialis;

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ژورنال

عنوان ژورنال: Jurnal Kedokteran Gigi Universitas Padjadjaran

سال: 2022

ISSN: ['2549-6514', '0854-6002']

DOI: https://doi.org/10.24198/jkg.v34i3.38504